Mathieu Sauthier Catalysis and Molecular Chemistry Department Catalysis and eco-compatible synthesis (CASECO) Professeur des Universités (Faculty researchers) Phone: (+33) 03 74 95 13 84 Mail: This email address is being protected from spambots. You need JavaScript enabled to view it. Address: Ecole Nationale Supérieure de Chimie de Lille Cité Scientifique, Bâtiment C7 - BP 90108 59652 Villeneuve d'Ascq Cedex France

Education

Current research interest :

Homogeneous catalysis toward organic synthesis
Atom efficiency – greener chemistry – polyols valorization

Chemistry of carbon monoxide Synthesis of compounds with a carbonyle function
(ketoesters, amides, esters, lactones, ketones, diketones ... ) Carbonylative suzuki coupling reactions Hydroformylation Alkoxycarbonylation Hydroesterification  ... Catalyst improvements / screening: Catalytic activity (TOF), selectivity and life time (TON).
	Saving synthetic and purification steps Domino carbonylative reactions: multiple bonds construction under “One pot” conditions. The construction of elaborated molecules is one step is targeted. Choice of catalysts / reactions conditions and substrates are carefully chosen in order to limit the importance of side reactions or catalyst poisoning.
Example of studied domino reaction:
4 new bonds in a “one pot” procedure !
Chemistry of 1,3-butadiene Clean catalytic etherification reactions with 1,3-butadiene ... Palladium catalysed telomerization reaction ...  under biphasic conditions: Synthesis of amphiphilic compounds derivred from agro-resources Nickel catalyzed hydroalkoxylation: Short chain grafting on a hydroxyl function           ... toward agro-based polyols valorization

Book chapters:

BOOK CHAPTER : Carbohydrate Chemistry : Vol. 40 ; 2014 – Royal Society of Chemistry -  Ed. : A. P. Rauter, T. Lindhorst, Y. Queneau
Chapter 5 : “From conventional to greener catalytic approaches for carbohydrates authentification”
M. Sauthier, A. Mortreux, I. Suisse

BOOK CHAPTER : Science of Synthesis: C-1 Building Blocks in Organic Synthesis; Vol. 1; 2014 - Thieme – Ed. P. W. N. M. van Leeuwen
Chapter 1.1.4 : “Nonconventional Reaction Media: Hydroformylation, Carbonylation, and Hydrocarbonylation of Alkenes”
A. Mortreux, M. Sauthier, E. Monflier, S. Tilloy

Bibliographie

Articles

Publications in the database: 50 (since 2005)

• 2023

• Efficient and sustainable one‐pot synthesis of α‐carbonyl homoallylic alcohols from benzaldehyde and allylic alcohols using both NHC and nickel catalysts.
  Homrani Yasmina, Mouhsine Bouchaib, Béthegnies Aurélien, El Amrani Mohamed Amin, Karim Abdallah, Suisse Isabelle, Sauthier Mathieu.
  ChemCatChem, (2023) DOI
   
• Catalytic hydroesterification of lignin: a versatile and efficient entry into fully biobased tunable materials.
  Buhaibeh Ruqaya, Richard Tiphaine, Gauvin Régis M., Sauthier Mathieu, Dumont Clément.
  Green Chemistry, vol. 25, pg. 1842-1851 (2023) DOI
   

• 2022

• Substituted N-heterocyclic carbene PEPPSI-type palladium complexes with different N-coordinated ligands: Involvement in the direct C H bond activation of heteroarenes derivatives with aryl bromide and their antimicrobial, anti-inflammatory and antioxidant activities.
  Slimani I., Boubakri L., Özdemir N., Mansour L., Özdemir I., Gürbüz N., YAŞAR S., Sauthier M., Hamdi N.
  Inorganica Chimica Acta, vol. 532, pg. 120747 (2022) DOI
   
• Synthesis, characterization and in vitro bioactivity studies of isoindolin‐1‐3‐phosophonate compounds.
  Jelali Hamida, Al Nasr Ibrahim S., Koko Waleed S., Khan Tariq A., Deniau Eric, Sauthier Mathieu, Alresheedi Faisal, Hamdi Naceur.
  Journal of Heterocyclic Chemistry, vol. 59, pg. 493-506 (2022) DOI
   
• The Selective Nickel-Catalyzed N-Allylation of C3-Unprotected Indoles under Mild and Clean Conditions .
  Mouhsine Bouchaib, Karim Abdallah, Dumont Clément, Saint Pol Anthony, Suisse Isabelle, Sauthier Mathieu.
  European Journal of Organic Chemistry, vol. 2022 (2022) DOI
   
• Ruthenium(II) complexes bearing benzimidazole-based N-heterocyclic carbene (NHC) ligands as potential antimicrobial, antioxidant, enzyme inhibition, and antiproliferative agents.
  Boubakri Lamia, Chakchouk-Mtiba Ahlem, Naouali Olfa, Mellouli Lotfi, Mansour Lamjed, Özdemir Ismail, Yaser Sedat, Sauthier Mathieu, Hamdi Naceur.
  Journal of Coordination Chemistry, vol. 75, pg. 645-667 (2022) DOI
   
• Synthesis and crystal structures of palladium complexes based on α-amino-oximes derived from (R)-limonene and their application in allylic alkylation of 1,3-dioxo compounds.
  Homrani Yasmina, El Amrani Mohamed Amin, Loxq Pauline, Capet Frédéric, Suisse Isabelle, Sauthier Mathieu.
  Comptes Rendus. Chimie, vol. 25, pg. 125-135 (2022) DOI
   

• 2021

• Reductive Hydroformylation of Isosorbide Diallyl Ether.
  Ternel Jérémy, Lopes Adrien, Sauthier Mathieu, Buffe Clothilde, Wiatz Vincent, Bricout Hervé, Tilloy Sébastien, Monflier Eric.
  Molecules, vol. 26, pg. 7322 (2021) DOI
   
• Synthesis and crystal structure of a new chiral α-aminooxime nickel(II) complex.
  Homrani Yasmina, Dahdouh Abdelaziz, El Amrani Mohamed Amin, Loxq Pauline, Capet Frédéric, Suisse Isabelle, Sauthier Mathieu.
  Acta Crystallographica Section E Crystallographic Communications, vol. 77, pg. 1116-1119 (2021) DOI
   
• Palladium catalyzed telomerization of bio-based polyols with atmospheric pressure bubbling butadiene.
  Peruzzo Deborah, Drelon Mathieu, Dumont Clément, Mortreux André, Suisse Isabelle, Sauthier Mathieu.
  Molecular Catalysis, vol. 502, pg. 111369 (2021) DOI
   
• Efficient and Clean Nickel Catalyzed α‐Allylation Reaction of Nitriles.
  Mouhsine Bouchaib, Karim Abdallah, Dumont Clément, Suisse Isabelle, Sauthier Mathieu.
  Advanced Synthesis < Catalysis, vol. 363, pg. 1457-1462 (2021) DOI
   

• 2020

• Enantioselective Nickel Catalyzed Butadiene Hydroalkoxylation with Ethanol: from Experimental Results to Kinetics Parameters.
  Mifleur Alexis, Suisse Isabelle, Mortreux André, Sauthier Mathieu.
  Catalysis Letters, vol. 151, pg. 27-35 (2020) DOI
   
• An Efficient Synthesis of Phthalimides and Their Biological Activities.
  Jelali H., Mansour L., Deniau E., Sauthier M., Hamdi N.
  Polycyclic Aromatic Compounds, vol. 42 (4), pg. 1806*18013 (2020) DOI
   
• The salt-free nickel-catalysed α-allylation reaction of ketones with allyl alcohol and diallylether.
  Mouhsine Bouchaib, Karim Abdallah, Dumont Clément, Sauthier Mathieu.
  Green Chemistry, vol. 22, pg. 950-955 (2020) DOI
   
• Visible-Light-Driven CarboxyLic Amine Protocol (CLAP) for the Synthesis of 2-Substituted Piperazines under Batch and Flow Conditions.
  Gueret Robin, Pelinski Lydie, Bousquet Till, Sauthier Mathieu, Ferey Vincent, Bigot Antony.
  Organic Letters, vol. 22, pg. 5157-5162 (2020) DOI
   
• Photocatalyzed Amidoarylation of 1,3‐Butadiene.
  Gosset Cyrille, Moncomble Aurélien, Dumont Clément, Pellegrini Sylvain, Bousquet Till, Sauthier Mathieu, Pélinski Lydie.
  Advanced Synthesis < Catalysis, (2020) DOI
   

• 2019

• Towards Selective Syntheses of Octadienylethers from the Butadiene Palladium‐catalyzed Telomerization with Polyols in Aqueous Biphasic Medium.
  Drelon Mathieu, Mérel Delphine S., Mortreux André, Suisse Isabelle, Sauthier Mathieu.
  ChemCatChem, vol. 11, pg. 1742-1746 (2019) DOI
   
• The Palladium‐Catalyzed Carboxytelomerization of Butadiene with Agrobased Alcohols and Polyols.
  Wilson Emma, Dumont Clément, Drelon Mathieu, Suisse Isabelle, Penverne Christophe, Sauthier Mathieu.
  ChemSusChem, vol. 12 (11), pg. 2457-2461 (2019) DOI
   
• Catalytic dehydration of sorbitol to isosorbide in the presence of metal tosylate salts and metallized sulfonic resins.
  Dussenne Corentin, Wyart Hervé, Wiatz Vincent, Suisse Isabelle, Sauthier Mathieu.
  Molecular Catalysis, vol. 463, pg. 61-66 (2019) DOI
   

• 2018

• The Palladium-Catalyzed Carbonylative Telomerization Reaction with Phenols, Polyphenols and Kraft Lignin.
  Dumont Clément, Belva Frederic, Gauvin Regis M., Sauthier Mathieu.
  ChemSusChem, vol. 11, pg. 3917-3922 (2018) DOI
   
• Efficient in situ N-heterocyclic carbene palladium(ii) generated from Pd(OAc)2 catalysts for carbonylative Suzuki coupling reactions of arylboronic acids with 2-bromopyridine under inert conditions leading to unsymmetrical arylpyridine ketones: synthesis, characterization and cytotoxic activities.
  Touj Nedra, Al-Ayed Abdullah S., Sauthier Mathieu, Mansour Lamjed, Harrath Abdel Halim, Al-Tamimi Jamil, Özdemir Ismail, Yaşar Sedat, Hamdi Naceur.
  RSC Advances, vol. 8, pg. 40000-40015 (2018) DOI
   
• Palladium-Catalyzed Functionalization of Kraft Lignin: Ether Linkages through the Telomerization Reaction.
  Dumont Clément, Gauvin Régis M., Belva Frédéric, Sauthier Mathieu.
  ChemSusChem, vol. 11, pg. 1649-1655 (2018) DOI
   

• 2017

• Synthesis of isosorbide: an overview of challenging reactions.
  Dussenne C., Delaunay T., Wiatz V., Wyart H., Suisse I., Sauthier M.
  Green Chemistry, vol. 19, pg. 5332-5344 (2017) DOI
   
• Deciphering the Mechanism of the Nickel-Catalyzed Hydroalkoxylation Reaction: A Combined Experimental and Computational Study.
  Mifleur Alexis, Mérel Delphine S., Mortreux André, Suisse Isabelle, Capet Frédéric, Trivelli Xavier, Sauthier Mathieu, Macgregor Stuart A.
  ACS Catalysis, vol. 7, pg. 6915-6923 (2017) DOI
   
• Synthesis of C4 chain glyceryl ethers via nickel-catalyzed butadiene hydroalkoxylation reaction.
  Mifleur Alexis, Mortreux André, Suisse Isabelle, Sauthier Mathieu.
  Molecular Catalysis, vol. 427, pg. 25-30 (2017) DOI
   
• Nickel-Catalyzed α-Allylation of Aldehydes and Tandem Aldol Condensation/Allylation Reaction with Allylic Alcohols.
  Bernhard Yann, Thomson Brodie, Ferey Vincent, Sauthier Mathieu.
  Angewandte Chemie International Edition, vol. 56, pg. 7460-7464 (2017) DOI
   

• 2016

• Synthesis of Short-Chain Alkenyl Ethers from Primary and Bio-sourced Alcohols via the Nickel-Catalyzed Hydroalkoxylation Reaction of Butadiene and Derivatives.
  Mifleur Alexis, Ledru Hélène, Lopes Adrien, Suisse Isabelle, Mortreux André, Sauthier Mathieu.
  Advanced Synthesis < Catalysis, vol. 358, pg. 110-121 (2016) DOI
   
• Telomerization of 1,3-butadiene with glycerol carbonate and subsequent ring-opening lactone co-polymerization.
  Ibn El Alami Mohammed Samir, Suisse Isabelle, Fadlallah Sami, Sauthier Mathieu, Visseaux Marc.
  Comptes Rendus Chimie, vol. 19, pg. 299-305 (2016) DOI
   
• Nickel-Catalysed Bis-Allylation of Activated Nucleophiles with Allyl ­Alcohol.
  Blieck Rémi, Azizi Mohamed Salah, Mifleur Alexis, Roger Maxime, Persyn Clément, Sauthier Mathieu, Bonin Hélène.
  European Journal of Organic Chemistry, vol. 2016, pg. 1194-1198 (2016) DOI
   
• Nickel(0)-CatalyzedN-Allylation of Amides andp-Toluenesulfonamide with Allylic Alcohols under Neat and Neutral Conditions.
  Azizi Mohamed Salah, Edder Youssef, Karim Abdallah, Sauthier Mathieu.
  European Journal of Organic Chemistry, vol. 2016, pg. 3796-3803 (2016) DOI
   

• 2015

• Palladium-catalyzed hydroesterification of olefins with isosorbide in standard and Brønsted acidic ionic liquids.
  Boulanger Jérôme, Seingeot Adeline, Léger Bastien, Pruvost Romain, Ibert Mathias, Mortreux André, Chenal Thomas, Sauthier Mathieu, Ponchel Anne, Monflier Eric.
  Catalysis Communications, vol. 69, pg. 143-146 (2015) DOI
   
• Biphasic Palladium-Catalyzed Hydroesterification in a Polyol Phase: Selective Synthesis of Derived Monoesters.
  Pruvost Romain, Boulanger Jérôme, Léger Bastien, Ponchel Anne, Monflier Eric, Ibert Mathias, Mortreux André, Sauthier Mathieu.
  ChemSusChem, vol. 8, pg. 2133-2137 (2015) DOI
   

• 2014

• Synthesis of 1,4:3,6-Dianhydrohexitols Diesters from the Palladium-Catalyzed Hydroesterification Reaction.
  Pruvost Romain, Boulanger Jérôme, Léger Bastien, Ponchel Anne, Monflier Eric, Ibert Mathias, Mortreux André, Chenal Thomas, Sauthier Mathieu.
  ChemSusChem, vol. 7 (11), pg. 3157-3163 (2014) DOI
   
• Transition Metal-Mediated Direct CH Arylation of Heteroarenes Involving Aryl Radicals.
  Bonin Hélène, Sauthier Mathieu, Felpin François-Xavier.
  Advanced Synthesis < Catalysis, vol. 356, pg. 645-671 (2014) DOI
   

• 2013

• Nickel-Catalysed Hydroalkoxylation Reaction of 1,3-Butadiene: Ligand Controlled Selectivity for the Efficient and Atom-Economical Synthesis of Alkylbutenyl Ethers.
  Bigot Sandra, El Alami Mohammed Samir Ibn, Mifleur Alexis, Castanet Yves, Suisse Isabelle, Mortreux André, Sauthier Mathieu.
  Chemistry - A European Journal, vol. 19, pg. 9785-9788 (2013) DOI
   
• Synthesis of α-Alkylated β-Ketoesters by Alkoxycarbonylation/Michael Addition Domino Reaction.
  Wahl Benoit, Philipson Yann, Bonin Hélène, Mortreux André, Sauthier Mathieu.
  The Journal of Organic Chemistry, vol. 78, pg. 1547-1552 (2013) DOI
   

• 2012

• Straightforward Synthesis of Allylated Keto Esters: The Palladium-Catalysed Haloketone Alkoxycarbonylation/ Allylation Domino Reaction.
  Wahl Benoit, Giboulot Steven, Mortreux André, Castanet Yves, Sauthier Mathieu, Liron Frédéric, Poli Giovanni.
  Advanced Synthesis < Catalysis, vol. 354, pg. 1077-1083 (2012) DOI
   
• Pd-catalyzed domino carbonylative–decarboxylative allylation: an easy and selective monoallylation of ketones.
  Giboulot Steven, Liron Frédéric, Prestat Guillaume, Wahl Benoit, Sauthier Mathieu, Castanet Yves, Mortreux André, Poli Giovanni.
  Chemical Communications, vol. 48, pg. 5889 (2012) DOI
   
• Effect of Chain Unsaturation on the Self-Association of Tri- and Tetraethylene Glycol Octyl Ethers Obtained by Butadiene Telomerization.
  Lai Jonathan, Molinier Valérie, Sauthier Mathieu, Moity Laurianne, Castanet Yves, Mortreux André, Aubry Jean-Marie.
  Langmuir, vol. 28, pg. 242-250 (2012) DOI
   
• A General and Efficient Method for the Alkoxycarbonylation of α-Chloro Ketones.
  Wahl Benoit, Bonin Hélène, Mortreux André, Giboulot Steven, Liron Frédéric, Poli Giovanni, Sauthier Mathieu.
  Advanced Synthesis < Catalysis, vol. 354, pg. 3105-3114 (2012) DOI
   

• 2011

• Telomerisation of 1,3-Butadiene with 1,4:3,6-Dianhydrohexitols: An Atom-Economic and Selective Synthesis of Amphiphilic Monoethers from Agro-Based Diols.
  Lai Jonathan, Bigot Sandra, Sauthier Mathieu, Molinier Valérie, Suisse Isabelle, Castanet Yves, Aubry Jean-Marie, Mortreux André.
  ChemSusChem, vol. 4, pg. 1104-1111 (2011) DOI
   

• 2010

• Organometallic catalysis: From concepts to selected applications.
  Sauthier Mathieu, Zinck Philippe, Mortreux André.
  Comptes Rendus Chimie, vol. 13, pg. 304-314 (2010) DOI
   
• Telomerisation of 1,3-butadiene with glycerol under aqueous biphasic conditions: Influence of the reaction conditions on the products distribution.
  Bigot Sandra, Lai Jonathan, Suisse Isabelle, Sauthier Mathieu, Mortreux André, Castanet Yves.
  Applied Catalysis A: General, vol. 382, pg. 181-189 (2010) DOI
   
• New Synthesis of Furans: the Rhodium-Catalysed Carbonylative Addition of Arylboronic Acids to Propargylic Alcohols/ Cyclisation Sequence.
  Dheur Julien, Sauthier Mathieu, Castanet Yves, Mortreux André.
  Advanced Synthesis < Catalysis, vol. 352, pg. 557-561 (2010) DOI
   

• 2009

• Palladium-Catalysed Carbonylative Cross-Coupling Reactions of Aryl Iodides and Vinyl Boron Derivatives as a Straightforward Route to Aryl Vinyl Ketones.
  Castanet Yves, Sauthier Mathieu, Pirez Cyril, Dheur Julien, Mortreux André.
  Synlett, vol. 2009, pg. 1745-1748 (2009) DOI
   
• Carbonylative 1,4-addition of potassium aryltrifluoroborates to vinyl ketones.
  Sauthier Mathieu, Lamotte Nicolas, Dheur Julien, Castanet Yves, Mortreux André.
  New Journal of Chemistry, vol. 33, pg. 969 (2009) DOI
   
• Aqueous hydroformylation reaction mediated by randomly methylated β-cyclodextrin: How substitution degree influences catalytic activity and selectivity.
  Legrand François-Xavier, Sauthier Mathieu, Flahaut Christophe, Hachani Johan, Elfakir Claire, Fourmentin Sophie, Tilloy Sébastien, Monflier Eric.
  Journal of Molecular Catalysis A: Chemical, vol. 303, pg. 72-77 (2009) DOI
   

• 2008

• 1,4-Conjugate addition reaction catalyzed by a homogeneous rhodium catalyst entrapped in hydrophobized ordered mesoporous silica.
  Handa Paul, Holmberg Krister, Sauthier Mathieu, Castanet Yves, Mortreux André.
  Microporous and Mesoporous Materials, vol. 116, pg. 424-431 (2008) DOI
   

• 2005

• Rhodium Complexes Non-Covalently Bound to Cyclodextrins: Novel Water-Soluble Supramolecular Catalysts for the Biphasic Hydroformylation of Higher Olefins.
  Sueur Benoît, Leclercq Loïc, Sauthier Mathieu, Castanet Yves, Mortreux André, Bricout Hervé, Tilloy Sébastien, Monflier Eric.
  Chemistry - A European Journal, vol. 11, pg. 6228-6236 (2005) DOI
   
• Two-Phase Hydroformylation of Higher Olefins Using Randomly Methylated ?-Cyclodextrin as Mass Transfer Promoter: A Smart Solution for Preserving the Intrinsic Properties of the Rhodium/Trisulfonated Triphenylphosphine Catalytic System.
  Leclercq Loïc, Sauthier Mathieu, Castanet Yves, Mortreux André, Bricout Hervé, Monflier Eric.
  Advanced Synthesis < Catalysis, vol. 347, pg. 55-59 (2005) DOI